Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379821 | 0.81 | KMT2A (0.48) | ALOX15PTGDR2HPGDKDM4EALDH1A1 | |
| SCHEMBL9380685 | 0.79 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL9378807 | 0.76 | ALOX15 (0.66) | ALOX15PTGDR2HPGDKDM4EALDH1A1 | |
| SCHEMBL9380227 | 0.74 | TDP1 (0.46) | ALOX15PTGDR2HPGDKDM4EALDH1A1 | |
| SCHEMBL29567556 | 0.72 | TDP1 (0.49) | ALOX15PTGDR2KDM4ETDP1KMT2A | |
| SCHEMBL1611157 | 0.72 | TDP1 (0.49) | ALOX15PTGDR2KDM4ETDP1KMT2A | |
| SCHEMBL1279945 | 0.71 | SMN1; SMN2 (0.63) | PTGDR2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL9379284 | 0.69 | PKM (0.40) | ALOX15PTGDR2HPGDKDM4EALDH1A1 | |
| SCHEMBL9386270 | 0.68 | MMP13 (0.44) | HPGDKDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL9378776 | 0.68 | TDP1 (0.54) | ALOX15PTGDR2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026700-A | Certain quinolines and thienopyridines as excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | claimed |
| EP-0398283-B1 | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5112821-A | Excitatory amino acid antagonists which are certain thienopyridives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5026700-A | Certain quinolines and thienopyridines as excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0398283-A1 | Excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-11-22 | — | — | EP | disclosed |