Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798098 | 0.95 | — | — | |
| SCHEMBL16758707 | 0.95 | CA1 (0.42) | — | |
| SCHEMBL6967365 | 0.91 | CA1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL3541821 | 0.87 | — | — | |
| SCHEMBL25345297 | 0.86 | CA1 (0.31) | — | |
| Potassium Ion SCHEMBL1466554 | 0.86 | CA1 (0.31) | — | |
| Lithium Ion SCHEMBL1997803 | 0.86 | CA1 (0.31) | — | |
| Lithium Ion SCHEMBL31729498 | 0.86 | — | — | |
| SCHEMBL15212305 | 0.75 | TSHR (0.38) | — | |
| Tetramethylammonium Ion SCHEMBL1995407 | 0.75 | CHRNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4270264-A | — | — | None | — | — | JP | disclosed |
| US-7875692-B2 | high biocompatibility and moisture retention; useful polymer for variety of applications such as artificial organs, biomembranes, coating agents for medical tools, drug delivery, and as cosmetic ingredients | SHISEIDO COMPANY, LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| EP-1493754-B1 | POLYSACCHARIDE CONTAINING PHOSPHORYLCHOLINE GROUP AND PROCESS FOR PRODUCING THE SAME | SHISEIDO CO LTD (JP) | 2008-06-25 | — | — | EP | disclosed |
| US-7348424-B2 | Polysaccharide containing phosphorylcholine group and process for producing the same | SHISEIDO COMPANY, LTD. (JP) | 2008-03-25 | — | — | US | disclosed |
| US-20060020098-A1 | Polysiloxane having phosphorylcholine group and process for producing the same | SHISEIDO CO., LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
| US-20050222405-A1 | Polysaccharide containing phosphorylcholine group and process for producing the same | SHISEIDO COMPANY, LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1568729-A1 | POLYSILOXANE HAVING PHOSPHORYLCHOLINE GROUP AND PROCESS FOR PRODUCING THE SAME | SHISEIDO COMPANY, LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| EP-1493754-A1 | POLYSACCHARIDE CONTAINING PHOSPHORYLCHOLINE GROUP AND PROCESS FOR PRODUCING THE SAME | SHISEIDO COMPANY, LTD. (JP) | 2005-01-05 | — | — | EP | disclosed |
| JP-H04270264-A | SEROTONIN 5HT1A AGONIST | MERRELL DOW PHARMACEUT INC | 1992-09-25 | — | — | JP | disclosed |