Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410454 | 0.88 | MEN1 (0.46) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL8728965 | 0.86 | THRB (0.62) | MEN1KMT2AMAPTTHRBMAPK1 | |
| SCHEMBL7267419 | 0.82 | HTR7 (0.48) | MAPTKDM4EHTR7TSHR | |
| SCHEMBL7268609 | 0.74 | HTR7 (0.46) | MAPTMAPK1KDM4EHTR7TSHR | |
| SCHEMBL7268521 | 0.73 | ADRA1D (0.50) | MAPTKDM4EHTR7TSHR | |
| SCHEMBL8604985 | 0.73 | MEN1 (0.47) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL21855757 | 0.72 | ADAMTS5 (0.58) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL3729013 | 0.70 | CXCR3 (0.75) | MAPTTP53THRBLMNAKDM4E | |
| SCHEMBL7267422 | 0.70 | HTR7 (0.42) | MAPTKDM4EHTR7TSHR | |
| SCHEMBL30964241 | 0.69 | HTR1A (0.51) | MEN1KMT2AMAPTTHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |