Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408929 | 0.82 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2TGM2HDAC6HDAC3 | |
| SCHEMBL8551790 | 0.78 | MAPT (0.39) | TGM2 | |
| SCHEMBL8551807 | 0.76 | TGM2 (0.43) | TGM2GAAALDH1A1TSHRMAPK1 | |
| SCHEMBL8549538 | 0.74 | GRIK1 (0.46) | ZDHHC20ZDHHC2TGM2HDAC6HDAC3 | |
| SCHEMBL8549459 | 0.74 | PYGL (0.52) | TGM2PYGL | |
| SCHEMBL8547344 | 0.74 | TGM2 (0.38) | ZDHHC20ZDHHC2TGM2HDAC6HDAC3 | |
| SCHEMBL8550858 | 0.74 | ALDH1A1 (0.47) | TGM2HDAC1ALDH1A1 | |
| SCHEMBL8551077 | 0.74 | RAB9A (0.37) | ZDHHC20ZDHHC2TGM2GAAALDH1A1 | |
| SCHEMBL8545460 | 0.73 | ALDH1A1 (0.34) | TGM2GAAALDH1A1TSHRMAPK1 | |
| SCHEMBL8551267 | 0.72 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TGM2HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |