Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | DRD3 | P35462 | 7/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9409521 | 0.87 | DRD2 (0.53) | DRD2DRD3NAMPTCYP46A1F10 | |
| SCHEMBL9023914 | 0.85 | SMN1; SMN2 (0.51) | DRD2DRD3CYP46A1GAA | |
| SCHEMBL9409478 | 0.76 | ITGB3 (0.45) | NAMPTCYP46A1F10LMNAGAA | |
| SCHEMBL9409519 | 0.74 | F10 (0.59) | F10LMNAF2 | |
| SCHEMBL8838094 | 0.74 | SMN1; SMN2 (0.51) | CYP46A1GAA | |
| SCHEMBL8633130 | 0.73 | F10 (0.52) | F10LMNAGAA | |
| SCHEMBL9409485 | 0.73 | ROCK2 (0.51) | CYP46A1 | |
| Hydrochloric Acid SCHEMBL9023569 | 0.73 | HTR7 (0.48) | DRD2DRD3 | |
| SCHEMBL9409563 | 0.73 | ITGB3 (0.56) | NAMPTCYP46A1F10LMNAGAA | |
| Hydrochloric Acid SCHEMBL9409431 | 0.73 | ITGB3 (0.46) | DRD2DRD3NAMPTCYP46A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |