Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286430 | 0.90 | EPHX1 (0.42) | EPHX1CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL13681843 | 0.90 | EPHX1 (0.42) | EPHX1CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL9975574 | 0.87 | — | — | |
| SCHEMBL28794840 | 0.87 | — | — | |
| SCHEMBL3834863 | 0.87 | — | — | |
| SCHEMBL13627727 | 0.87 | — | — | |
| SCHEMBL4650689 | 0.86 | ALDH1A1 (0.46) | EPHX1CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL11279011 | 0.86 | EPHX1 (0.53) | EPHX1ALDH1A1MMP1KDM4E | |
| SCHEMBL23672561 | 0.85 | — | — | |
| SCHEMBL12448169 | 0.85 | EPHX1 (0.48) | EPHX1CYP2D6CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042550-B2 | Leave-on hair treatment compositions | L'OREAL (FR) | 2024-07-23 | — | — | US | claimed |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-18 | — | — | US | claimed |
| WO-2024073637-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-04 | — | — | WO | claimed |
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | L'OREAL (FR) | 2022-08-02 | — | — | US | claimed |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | L'OREAL (FR) | 2022-04-12 | — | — | US | claimed |
| WO-2021056665-A1 | GEMINI SURFACTANT FOR OIL DISPLACEMENT, BINARY COMBINATION SYSTEM FOR OIL DISPLACEMENT, AND PREPARATION METHOD FOR AND APPLICATION OF GEMINI SURFACTANT | 中国石油天然气股份有限公司 | 2021-04-01 | — | — | WO | claimed |
| EP-2988830-B1 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | OREAL (FR) | 2021-03-17 | — | — | EP | claimed |
| EP-2916808-B1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | OREAL (FR) | 2019-06-26 | — | — | EP | claimed |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2019-06-06 | — | — | US | claimed |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | L'OREAL (FR) | 2019-04-25 | — | — | US | claimed |
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| US-20060127337-A1 | Process for relaxing keratin fibres | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| WO-2006056491-A1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | L'ORÉAL (FR) | 2006-06-01 | — | — | WO | claimed |
| EP-1661551-A2 | Method of straightening keratin fibres with heating means and a denaturant agent | L'OREAL (FR) | 2006-05-31 | — | — | EP | claimed |
| EP-1661550-A1 | Cosmetic and/or dermatological composition comprising urea compound | L'OREAL, S.A. (FR) | 2006-05-31 | — | — | EP | claimed |
| US-20060111490-A1 | Composition comprising a urea compound | L'OREAL (FR) | 2006-05-25 | — | — | US | claimed |
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | CUTA, S100A11, KRT18 | EPHX1 981/4885CYP2D6 1213/4885CYP2C19 2407/4885 |
| US-12042550-B2 | Leave-on hair treatment compositions | ALG3, DEGS1, DSG1 | EPHX1 2277/4885CYP2D6 3404/4885CYP2C19 2546/4885 |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | H1-0, KRT18, CCNE1 | EPHX1 912/4885CYP2D6 1403/4885CYP2C19 2524/4885 |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | KRT18, OAT, CKMT1A; CKMT1B | EPHX1 4323/4885CYP2D6 4698/4885CYP2C19 4541/4885 |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | ALG3, DEGS1, DSG1 | EPHX1 2277/4885CYP2D6 3404/4885CYP2C19 2546/4885 |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | SLC14A1, CTRL, URB2 | EPHX1 2373/4885CYP2D6 1043/4885CYP2C19 1587/4885 |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | KRT18, OAT, CKMT1A; CKMT1B | EPHX1 4323/4885CYP2D6 4698/4885CYP2C19 4541/4885 |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | KRT18, CUTA, MARK1 | EPHX1 4150/4885CYP2D6 4225/4885CYP2C19 3951/4885 |
| US-20060127337-A1 | Process for relaxing keratin fibres | KRT18, TPM4, MYLK | EPHX1 4336/4885CYP2D6 3674/4885CYP2C19 4045/4885 |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | CUTA, TYR, ADH7 | EPHX1 2487/4885CYP2D6 2270/4885CYP2C19 2289/4885 |
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | KRT18, CUTA, PUF60 | EPHX1 4454/4885CYP2D6 4052/4885CYP2C19 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.