Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.42 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.36 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.34 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625563 | 0.91 | TSHR (0.48) | CA2CA1KDM4EALDH1A1HPGD | |
| SCHEMBL29637851 | 0.91 | TSHR (0.48) | CA2CA1KDM4EALDH1A1HPGD | |
| SCHEMBL8464005 | 0.84 | CA1 (0.40) | CA2CA1KDM4EALDH1A1HPGD | |
| Pyromellitic Acid SCHEMBL6263960 | 0.82 | KDM4E (0.48) | CA2CA1KDM4EALDH1A1HPGD | |
| SCHEMBL872023 | 0.79 | CA1 (0.39) | CA2CA1KDM4EALDH1A1HPGD | |
| SCHEMBL30596154 | 0.77 | SORT1 (0.40) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL7732128 | 0.76 | KDM4E (0.42) | CA2CA1KDM4EALDH1A1HPGD | |
| Pyromellitic Acid SCHEMBL10454935 | 0.76 | KDM4E (0.42) | CA2CA1KDM4EALDH1A1HPGD | |
| Pyromellitic Acid SCHEMBL9693112 | 0.76 | KDM4E (0.42) | CA2CA1KDM4EALDH1A1HPGD | |
| Pyromellitic Acid SCHEMBL1150971 | 0.76 | KDM4E (0.42) | CA2CA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140374733-A1 | PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-0409172-B1 | Process for dimerizing aromatic halogen compounds | MITSUBISHI CHEM IND (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0318634-B1 | PROCESS FOR DIMERIZATION OF AROMATIC HALIDE COMPOUNDS | MITSUBISHI KASEI CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| US-5095144-A | Catalytic, dehalogenation | MITSUBISHI KASEI CORPORATION (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0409172-A2 | Process for dimerizing aromatic halogen compounds | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4900843-A | Method for dimerization of aromatic halide compounds | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0318634-A1 | Process for dimerization of aromatic halide compounds | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | disclosed |