Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062089 | 0.87 | ALDH1A1 (0.46) | KDM4EMAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL1532744 | 0.79 | L3MBTL1 (0.39) | MEN1KDM4EMAPTKMT2AMAPK1 | |
| SCHEMBL7209808 | 0.70 | CA2 (0.46) | MEN1KDM4EMAPTKMT2AMAPK1 | |
| SCHEMBL7197852 | 0.67 | SIRT2 (0.49) | MEN1MAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL5666286 | 0.66 | RAB9A (0.35) | KDM4ERAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10624676 | 0.65 | KMT2A (0.45) | MEN1KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL9831088 | 0.65 | KDM4E (0.41) | MEN1KDM4EMAPTKMT2AMAPK1 | |
| SCHEMBL7295427 | 0.64 | PLAT (0.32) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2524847 | 0.63 | CHRNB2 (0.52) | MEN1KDM4EMAPTKMT2AMAPK1 | |
| SCHEMBL9831252 | 0.63 | KDM4E (0.46) | MEN1KDM4EMAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |