Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 10/20 | 0.54 |
| ▸ | LOX | P28300 | 7/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238350 | 0.87 | LOXL2 (0.59) | MAPK8MAPK10LOXL2LOXF2 | |
| SCHEMBL27569210 | 0.83 | OPRK1 (0.49) | MAPK8MAPK10PARP10LOXL2LOX | |
| SCHEMBL28439623 | 0.81 | KDM4E (0.55) | MAPK8MAPK10LOXL2LOXNPC1 | |
| Benzamide SCHEMBL27324266 | 0.81 | PARP10 (0.59) | MAPK8MAPK10PARP10LOXL2F2 | |
| SCHEMBL27569211 | 0.79 | OPRM1 (0.47) | MAPK8MAPK10LOXL2LOXOPRK1 | |
| SCHEMBL3702576 | 0.79 | OPRM1 (0.72) | OPRK1KCNH2OPRM1OPRD1 | |
| SCHEMBL7635169 | 0.79 | LOXL2 (0.67) | LOXL2LOXNPC1RAB9A | |
| SCHEMBL1758360 | 0.79 | PARP10 (0.57) | PARP10TNKSPARP15PARP14TNKS2 | |
| SCHEMBL23189218 | 0.78 | TNKS (0.58) | MAPK8MAPK10PARP10LOXL2LOX | |
| SCHEMBL445784 | 0.76 | NNMT (0.56) | PARP10LOXL2LOXPARP2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-01-13 | — | — | US | claimed |
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-01-13 | — | — | US | disclosed |
| EP-0488474-B1 | Herbicidal carboxamide derivatives | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | MAPK8 960/4885MAPK10 1375/4885PARP10 1592/4885 |
| US-20110009437-A1 | CARBOXAMIDE-HETEROARYL DERIVATIVES FOR THE TREATMENT OF DIABETES | GLS, GCKR, HK1 | MAPK8 1493/4885MAPK10 2258/4885PARP10 3777/4885 |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | MAPK8 4455/4885MAPK10 3297/4885PARP10 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.