SCHEMBL945295

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL750563	0.85	SLC6A2 (0.59)	SLC6A2SLC6A4SLC6A3ALDH1A1NPSR1
	SCHEMBL3467608	0.77	MAPT (0.63)	ALDH1A1NPSR1HPGDL3MBTL1SMN1; SMN2
	SCHEMBL11356266	0.76	NPC1 (0.49)	ALDH1A1NPSR1HPGDL3MBTL1SMN1; SMN2
	SCHEMBL16261615	0.76	LMNA (0.54)	ALDH1A1NPSR1L3MBTL1SMN1; SMN2NPC1
	SCHEMBL1662507	0.76	L3MBTL1 (0.41)	ALDH1A1NPSR1HPGDL3MBTL1SMN1; SMN2
	SCHEMBL1916178	0.76	ALDH1A1 (0.52)	ALDH1A1NPSR1L3MBTL1SMN1; SMN2NPC1
	SCHEMBL9467120	0.76	NPSR1 (0.43)	ALDH1A1NPSR1HPGDPOLBL3MBTL1
	SCHEMBL6320855	0.76	ALDH1A1 (0.53)	ALDH1A1NPSR1HPGDPOLBL3MBTL1
	SCHEMBL171307	0.75	ALDH1A1 (0.54)	ALDH1A1NPSR1HPGDPOLBL3MBTL1
	SCHEMBL4200328	0.74	PGR (0.51)	ALDH1A1HPGDL3MBTL1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.