Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270185 | 0.83 | HPGD (0.40) | ALOX5MMP1MMP13 | |
| SCHEMBL9269765 | 0.81 | LMNA (0.36) | ALOX5 | |
| SCHEMBL9458668 | 0.80 | CYP1A2 (0.34) | ALOX5 | |
| SCHEMBL9458222 | 0.79 | ALOX5 (0.36) | HTR1AHTR3AALOX5MMP1MMP13 | |
| SCHEMBL9385364 | 0.74 | MAPT (0.40) | ALOX5 | |
| SCHEMBL9101868 | 0.69 | P2RX7 (0.37) | ALOX5 | |
| SCHEMBL9458464 | 0.69 | ALOX5 (0.32) | HTR1AHTR3AALOX5 | |
| SCHEMBL9083286 | 0.68 | P4HB (0.32) | — | |
| SCHEMBL9380947 | 0.67 | GRIN2B (0.32) | ALOX5 | |
| SCHEMBL9458371 | 0.67 | ALOX5 (0.45) | ALOX5MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |