Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817859 | 0.78 | TNKS2 (0.44) | HCAR2ALDH1A1HPGDADORA2AL3MBTL1 | |
| SCHEMBL9190029 | 0.74 | ALDH1A1 (0.43) | HCAR2ALDH1A1 | |
| SCHEMBL6440045 | 0.72 | HCAR2 (0.43) | HCAR2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9192192 | 0.71 | NPC1 (0.49) | HCAR2ALDH1A1KMT2A | |
| SCHEMBL9195013 | 0.71 | HCAR2 (0.37) | HCAR2 | |
| SCHEMBL9191469 | 0.71 | HCAR2 (0.47) | HCAR2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9195100 | 0.70 | RAB9A (0.59) | HCAR2MEN1KMT2A | |
| SCHEMBL9194026 | 0.70 | HCAR2 (0.44) | HCAR2ALDH1A1 | |
| SCHEMBL5332492 | 0.69 | NUDT1 (0.50) | NPSR1ALDH1A1HPGD | |
| SCHEMBL9191459 | 0.69 | HCAR2 (0.40) | HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| US-3895012-A | 2-Alkyl-4(3H)-pteridinone compounds and therapeutic compositions | BOEHRINGER MANNHEIM GMBH | 1975-07-15 | — | — | US | disclosed |
| US-3895012-A | 2-Alkyl-4(3H)-pteridinone compounds and therapeutic compositions | BOEHRINGER MANNHEIM GMBH | 1975-07-15 | — | — | US | disclosed |