Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502196 | 0.76 | CYP2D6 (0.47) | LMNAPKMGAAALDH1A1MEN1 | |
| SCHEMBL9504119 | 0.73 | CYP2D6 (0.44) | LMNAPKMGAAALDH1A1MEN1 | |
| SCHEMBL12726868 | 0.72 | CYP2D6 (0.76) | LMNAPKMGAAALDH1A1KMT2A | |
| SCHEMBL9501073 | 0.69 | GAA (0.59) | LMNAPKMGAAALDH1A1HTT | |
| SCHEMBL10386225 | 0.69 | ALDH1A1 (0.45) | LMNAPKMGAAALDH1A1MEN1 | |
| SCHEMBL9502176 | 0.68 | KDM4E (0.48) | LMNAPKMGAAALDH1A1HTT | |
| SCHEMBL9502157 | 0.68 | GPBAR1 (0.47) | LMNAGAAALDH1A1HTTMEN1 | |
| SCHEMBL3936533 | 0.67 | LMNA (0.61) | LMNAPKMGAAALDH1A1HTT | |
| SCHEMBL1350520 | 0.67 | LMNA (0.61) | LMNAPKMGAAALDH1A1HTT | |
| SCHEMBL1350186 | 0.66 | MEN1 (0.73) | LMNAPKMGAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |