SCHEMBL532243

SCHEMBL532243

OCCCc1ccc(O)cc1O

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 0.71
ALOX5 P09917 2/20 0.63
MEN1 O00255 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
MAPT P10636 1/20 0.63
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
HTT P42858 1/20 0.63
KMT2A Q03164 1/20 0.63
TDP1 Q9NUW8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1846489 0.92 TYR (0.70) TYRALOX5MEN1TP53CYP3A4
SCHEMBL4370686 0.89 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL30045833 0.86 TYR (0.77) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8398793 0.86 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8398763 0.86 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8401879 0.86 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8401997 0.86 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL950883 0.86 TYR (0.77) TYRALOX5MEN1TP53CYP3A4
SCHEMBL27903104 0.84 TYR (0.48) TYRALOX5MEN1TP53CYP3A4
SCHEMBL1397158 0.84 TYR (1.00) TYRALOX5MEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390343-B1 RESORCINOL DERIVATIVES FOR COSMETIC USE THEREOF OREAL (FR) 2020-10-14 EP disclosed
US-10457619-B2 Resorcinol derivatives for cosmetic use thereof L'OREAL (FR) 2019-10-29 US disclosed
WO-2017102536-A1 RESORCINOL DERIVATIVES FOR COSMETIC USE THEREOF L'OREAL (FR) 2017-06-22 WO disclosed
EP-1430147-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2013-05-22 EP disclosed
EP-1235938-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2012-02-08 EP disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 US disclosed
US-7662942-B2 Oligonucleotide probes containing two labels useful in hybridization assays Elitech Holdings, B.V. (NL) 2010-02-16 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
US-6727356-B1 AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION EPOCH PHARMACEUTICALS, INC. 2004-04-27 US disclosed
US-6699975-B2 OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION EPOCH BIOSCIENCES, INC. 2004-03-02 US disclosed
US-6653473-B2 Nucleotide sequences for use as diagnostic tool in genetic analysis EPOCH BIOSCIENCES, INC. 2003-11-25 US disclosed
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression EPOCH BIOSCIENCES, INC. (US) 2003-05-22 US disclosed
US-20030008304-A1 Fluorescent quenching detection reagents and methods EPOCH BIOSCIENCES, INC. (US) 2003-01-09 US disclosed
WO-2002099141-A1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2002-12-12 WO disclosed
US-20020155484-A1 Fluorescent quenching detection reagents and methods EPOCH PHARMACEUTICALS, INC. (US) 2002-10-24 US disclosed
EP-1235938-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS Epoch Biosciences, Inc. (US) 2002-09-04 EP disclosed
US-20020034754-A1 Fluorescent quenching detection reagents and methods ELITECHGROUP, INC. 2002-03-21 US disclosed
WO-2001042505-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2001-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008304-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B TYR 3084/4885ALOX5 2546/4885MEN1 4473/4885
US-20020034754-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B TYR 3084/4885ALOX5 2546/4885MEN1 4473/4885
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS DDX5, DDX21, DCLRE1B TYR 2808/4885ALOX5 2506/4885MEN1 4173/4885
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 TYR 1/4885ALOX5 63/4885MEN1 4836/4885
US-10457619-B2 Resorcinol derivatives for cosmetic use thereof CBR3, C1S, TYR TYR 3/4885ALOX5 135/4885MEN1 2157/4885
US-20020155484-A1 Fluorescent quenching detection reagents and methods IPO4, PTBP3, DDX5 TYR 908/4885ALOX5 2225/4885MEN1 4692/4885
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression DCLRE1B, SNRPE, ZFR TYR 4520/4885ALOX5 4369/4885MEN1 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.