SCHEMBL3683264

SCHEMBL3683264

CCOC(=O)C(N)Cc1ccc(O)c(I)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.52
THRA P10827 5/20 0.52
MEN1 O00255 7/20 0.51
KMT2A Q03164 7/20 0.51
LMNA P02545 5/20 0.51
PPARG P37231 3/20 0.51
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.51
GABRP O00591 1/20 0.51
GABRD O14764 1/20 0.51
ABCB11 O95342 1/20 0.51
F2 P00734 1/20 0.51
PCNA P12004 1/20 0.51
GABRA1 P14867 1/20 0.51
GABRB1 P18505 1/20 0.51
GABRG2 P18507 1/20 0.51
GABRB3 P28472 1/20 0.51
ADORA1 P30542 1/20 0.51
GABRA5 P31644 1/20 0.51
GABRA3 P34903 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683267 1.00 THRB (0.52) THRBTHRAMEN1KMT2ALMNA
SCHEMBL951158 0.87 THRB (0.52) THRBTHRAMEN1KMT2ALMNA
SCHEMBL9647408 0.87 THRB (0.52) THRBTHRAMEN1KMT2ALMNA
Etilevodopa SCHEMBL1069939 0.87 ALOX15 (0.64) MEN1KMT2ALMNAPPARGCYP2D6
Etilevodopa SCHEMBL584493 0.87 ALOX15 (0.64) MEN1KMT2ALMNAPPARGCYP2D6
Etilevodopa SCHEMBL29634876 0.87 ALOX15 (0.64) MEN1KMT2ALMNAPPARGCYP2D6
Hydrochloric Acid SCHEMBL7673388 0.86 ALDH1A1 (0.53) THRBTHRAMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL9662459 0.86 ALDH1A1 (0.53) THRBTHRAMEN1KMT2ALMNA
SCHEMBL8160664 0.86 THRB (0.51) THRBTHRAMEN1KMT2ALMNA
L-Tyrosine Ethylester SCHEMBL1574026 0.86 THRB (0.47) THRBTHRAMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11246884-B2 Inherently radiopaque polymeric products for embolotherapy RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-02-15 US disclosed
US-20190142863-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-05-16 US disclosed
EP-1673109-B1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY UNIV RUTGERS (US) 2019-03-20 EP disclosed
US-10206946-B2 Inherently radiopaque polymeric products for embolotherapy RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-19 US disclosed
US-10105467-B2 Biocompatible polymer compositions for tissue void filling RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2018-10-23 US disclosed
US-20180085396-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2018-03-29 US disclosed
US-9770465-B2 Inherently radiopaque polymeric products for embolotherapy RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-09-26 US disclosed
US-20150335783-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS FOR TISSUE VOID FILLING RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-11-26 US disclosed
EP-1923075-B1 Radiopaque polymeric stents UNIV RUTGERS (US) 2015-11-11 EP disclosed
US-20140255335-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2014-09-11 US disclosed
US-20100131037-A1 RADIOPAQUE POLYMERIC STENTS RUTGERS , THE STATE UNIVERSITY (US) 2010-05-27 US disclosed
EP-1673109-A4 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY UNIV RUTGERS (US) 2008-12-24 EP disclosed
EP-1955716-A2 Radiopaque polymeric stents Rutgers, The State University (US) 2008-08-13 EP disclosed
EP-1923075-A2 Radiopaque polymeric stents Rutgers, The State University (US) 2008-05-21 EP disclosed
EP-1789097-A2 RADIOPAQUE POLYMERIC STENTS Rutgers, The State University (US) 2007-05-30 EP disclosed
EP-1673109-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2006-06-28 EP disclosed
WO-2006022754-A2 RADIOPAQUE POLYMERIC STENTS RUTGERS, THE STATE UNIVERSITY (US) 2006-03-02 WO disclosed
US-20060034769-A1 Radiopaque polymeric stents RUTGERS, THE STATE UNIVERSITY (US) 2006-02-16 US disclosed
US-20050106119-A1 biocompatible, bioresorption polymer containing active materials; drug delivery to body cavity RUTGERS, THE STATE UNIVERSITY (US) 2005-05-19 US disclosed
WO-2005030268-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY (US) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10105467-B2 Biocompatible polymer compositions for tissue void filling PLOD3, AQP3, AQP1 THRB 916/4885THRA 813/4885MEN1 3491/4885
US-20140255335-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY CD47, FGB, ELANE THRB 3375/4885THRA 2936/4885MEN1 806/4885
US-20060034769-A1 Radiopaque polymeric stents TDO2, TYRO3, TH THRB 1188/4885THRA 1245/4885MEN1 3190/4885
US-10206946-B2 Inherently radiopaque polymeric products for embolotherapy CD47, FGB, ELANE THRB 3375/4885THRA 2936/4885MEN1 806/4885
US-20180085396-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY CD47, FGB, ELANE THRB 3375/4885THRA 2936/4885MEN1 806/4885
US-11246884-B2 Inherently radiopaque polymeric products for embolotherapy CD47, FGB, ELANE THRB 3375/4885THRA 2936/4885MEN1 806/4885
US-20190142863-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY CD47, FGB, ELANE THRB 3375/4885THRA 2936/4885MEN1 806/4885
US-20050106119-A1 biocompatible, bioresorption polymer containing active materials; drug delivery to body cavity CD47, CD68, MB THRB 2932/4885THRA 1965/4885MEN1 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.