Aminomethylbenzoic Acid

Aminomethylbenzoic Acid

SCHEMBL9523091

NCCCCCCC(=O)O.NCc1ccc(C(=O)O)cc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 3/20 0.57
LMNA P02545 2/20 0.57
THRB P10828 2/20 0.57
MEN1 O00255 2/20 0.57
PLG P00747 1/20 0.57
ALOX15 P16050 1/20 0.57
SLC6A2 P23975 1/20 0.57
RECQL P46063 1/20 0.57
SLC6A3 Q01959 1/20 0.57
CYP2D6 P10635 1/20 0.53
NFKB1 P19838 1/20 0.53
BLM P54132 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
HDAC3 O15379 3/20 0.45
HDAC6 Q9UBN7 3/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylbenzoic Acid SCHEMBL1201553 1.00 KMT2A (0.57) KMT2AALDH1A1LMNATHRBMEN1
Terephthalic Acid SCHEMBL262199 0.91 LMNA (0.68) KMT2AALDH1A1LMNATHRBMEN1
Terephthalic Acid SCHEMBL261197 0.91 LMNA (0.68) KMT2AALDH1A1LMNATHRBMEN1
Terephthalic Acid SCHEMBL11416033 0.91 LMNA (0.68) KMT2AALDH1A1LMNATHRBMEN1
Terephthalic Acid SCHEMBL5694411 0.85 LOXL2 (0.47) ALDH1A1SLC6A3HDAC3HDAC6HDAC4
Terephthalic Acid SCHEMBL7550600 0.85 LMNA (0.55) KMT2AALDH1A1LMNATHRBMEN1
Tranexamic Acid SCHEMBL5321519 0.84 PLG (0.48) KMT2AALDH1A1LMNATHRBMEN1
Stearic Acid SCHEMBL15899228 0.83 GPR84 (0.57) KMT2AALDH1A1LMNATHRBMEN1
Aminomethylbenzoic Acid SCHEMBL9344424 0.82 ALDH1A1 (0.60) KMT2AALDH1A1THRBMEN1RECQL
Terephthalic Acid SCHEMBL7046508 0.82 TSHR (0.60) KMT2AALDH1A1LMNATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458950-B1 STABILIZATION OF K2P PRO Roche Diagnostics GmbH (DE) 1993-09-15 EP claimed