Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524448 | 0.88 | NCEH1 (0.46) | RAB9ANPC1EPHX1 | |
| SCHEMBL9524773 | 0.82 | NCEH1 (0.49) | ALDH1A1 | |
| SCHEMBL9524918 | 0.81 | RAD52 (0.42) | GAASMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9525228 | 0.80 | HTT (0.47) | RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL9524931 | 0.79 | FAAH (0.44) | RAB9ANPC1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9523732 | 0.78 | RAB9A (0.55) | RAB9ANPC1GAAGPR139L3MBTL1 | |
| SCHEMBL9525680 | 0.78 | HTT (0.43) | RAB9AGAAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9524845 | 0.76 | PLA2G2A (0.41) | RAB9AEPHX1ALDH1A1 | |
| SCHEMBL9527439 | 0.76 | SMN1; SMN2 (0.43) | RAB9ANPC1EPHX1SMN1; SMN2LMNA | |
| SCHEMBL9525182 | 0.76 | GABRP (0.42) | TAAR1RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |