Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524448 | 0.87 | NCEH1 (0.46) | NCEH1MGLLEPHX1NPC1RAB9A | |
| SCHEMBL9524784 | 0.87 | TACR3 (0.46) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL9525182 | 0.86 | GABRP (0.42) | NCEH1 | |
| SCHEMBL9524845 | 0.86 | PLA2G2A (0.41) | NCEH1MGLLEPHX1RAB9A | |
| SCHEMBL9524847 | 0.82 | MAPT (0.42) | SMN1; SMN2CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL9524520 | 0.80 | LMNA (0.51) | SMN1; SMN2HPGDPOLBCYP1A2CYP2D6 | |
| SCHEMBL9524931 | 0.78 | FAAH (0.44) | SMN1; SMN2POLBCYP1A2CYP2C19LMNA | |
| SCHEMBL9525703 | 0.76 | RAB9A (0.43) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9523698 | 0.76 | RAB9A (0.49) | SMN1; SMN2LMNAEPHX1NPC1RAB9A | |
| SCHEMBL20169886 | 0.72 | NCEH1 (0.56) | SMN1; SMN2NCEH1HPGDPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |