Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524931 | 0.90 | FAAH (0.44) | NPC1RAB9A | |
| SCHEMBL9523698 | 0.88 | RAB9A (0.49) | EPHX1NPC1RAB9A | |
| SCHEMBL9525182 | 0.87 | GABRP (0.42) | NCEH1 | |
| SCHEMBL9527439 | 0.87 | SMN1; SMN2 (0.43) | NCEH1MGLLEPHX1NPC1RAB9A | |
| SCHEMBL9524845 | 0.87 | PLA2G2A (0.41) | NCEH1MGLLEPHX1RAB9A | |
| SCHEMBL9524784 | 0.85 | TACR3 (0.46) | NPC1RAB9ATACR3 | |
| SCHEMBL9525680 | 0.81 | HTT (0.43) | RAB9A | |
| SCHEMBL9524773 | 0.81 | NCEH1 (0.49) | NCEH1MGLL | |
| SCHEMBL9524918 | 0.80 | RAD52 (0.42) | — | |
| SCHEMBL9525228 | 0.78 | HTT (0.47) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |