Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | TNF | P01375 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525680 | 0.82 | HTT (0.43) | KMT2AMAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL9523908 | 0.82 | HPGD (0.46) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL9527700 | 0.82 | DDX3X (0.44) | MAPTDDX3XSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9525178 | 0.82 | NPC1 (0.43) | KMT2APOLBMAPTMEN1LMNA | |
| SCHEMBL9525725 | 0.82 | KMT2A (0.49) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL9527660 | 0.82 | ALDH1A1 (0.50) | KMT2AMAPTMEN1RAB9ANPC1 | |
| SCHEMBL9524822 | 0.81 | HIF1A (0.60) | KMT2APOLBMAPTMEN1TNF | |
| SCHEMBL9525121 | 0.80 | FLT3 (0.49) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9524899 | 0.79 | MAPT (0.50) | KMT2AMAPTMEN1RAB9AHTT | |
| SCHEMBL9524816 | 0.77 | MEN1 (0.41) | KMT2AMAPTMEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |