Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530054 | 0.88 | SIGMAR1 (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2HSD11B1 | |
| SCHEMBL9530276 | 0.80 | MAPT (0.45) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9455127 | 0.79 | DRD2 (0.46) | ALDH1A1LMNAMAPTSIGMAR1MEN1 | |
| SCHEMBL9697283 | 0.78 | KCNH2 (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9455139 | 0.75 | CCR3 (0.43) | LMNASMN1; SMN2HSD11B1SIGMAR1MEN1 | |
| SCHEMBL9530838 | 0.75 | L3MBTL1 (0.46) | ALDH1A1LMNAMAPTSIGMAR1 | |
| SCHEMBL9455326 | 0.72 | L3MBTL1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9646111 | 0.70 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL9529266 | 0.70 | DRD2 (0.53) | LMNAMAPTSIGMAR1MEN1KMT2A | |
| SCHEMBL9455304 | 0.70 | OPRM1 (0.43) | LMNAMAPTHSD11B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |
| EP-0359790-A1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989007596-A1 | NEW 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-08-24 | — | — | WO | disclosed |