Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697283 | 0.88 | KCNH2 (0.41) | L3MBTL1LMNAKDM4EMAPTACHE | |
| SCHEMBL9530054 | 0.83 | SIGMAR1 (0.39) | LMNAMAPTDRD4NPY1RALDH1A1 | |
| SCHEMBL9455127 | 0.76 | DRD2 (0.46) | LMNAKDM4EMAPTDRD4ALDH1A1 | |
| SCHEMBL9529274 | 0.75 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1SIGMAR1 | |
| SCHEMBL9530276 | 0.75 | MAPT (0.45) | LMNAMAPTDRD4NPY1RALDH1A1 | |
| SCHEMBL9530828 | 0.72 | KDM4E (0.45) | L3MBTL1LMNASLC6A7KDM4EDRD4 | |
| SCHEMBL9455326 | 0.69 | L3MBTL1 (0.47) | L3MBTL1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL9455304 | 0.67 | OPRM1 (0.43) | LMNAKDM4EMAPTDRD4OPRM1 | |
| Hydrochloric Acid SCHEMBL9455139 | 0.67 | CCR3 (0.43) | LMNAKDM4EDRD4OPRM1GPR119 | |
| SCHEMBL9455323 | 0.64 | OPRM1 (0.41) | LMNAKDM4EMAPTDRD4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |