Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530054 | 0.91 | SIGMAR1 (0.39) | MAPTNPY1RSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9455127 | 0.85 | DRD2 (0.46) | MAPTGAAALDH1A1LMNAKMT2A | |
| SCHEMBL9455326 | 0.81 | L3MBTL1 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9529274 | 0.80 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9697283 | 0.78 | KCNH2 (0.41) | MAPTALDH1A1LMNAKMT2ARAB9A | |
| SCHEMBL9455297 | 0.76 | KMT2A (0.42) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL9530838 | 0.75 | L3MBTL1 (0.46) | MAPTNPY1RALDH1A1LMNADRD4 | |
| SCHEMBL9455188 | 0.74 | L3MBTL1 (0.44) | MAPTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL6153220 | 0.73 | ALDH1A1 (0.66) | MAPTSMN1; SMN2GAAALDH1A1PKM | |
| SCHEMBL9530260 | 0.71 | SIGMAR1 (0.53) | SMN1; SMN2GAAPKMDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |