Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533768 | 0.81 | HTR1A (0.38) | ALDH1A1MAPK1MEN1KMT2ATSHR | |
| SCHEMBL9535109 | 0.69 | DRD2 (0.46) | ALDH1A1TDP1MEN1KMT2ADRD2 | |
| SCHEMBL2222984 | 0.61 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11001305 | 0.60 | KDM4E (0.44) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL14204664 | 0.60 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TDP1MAPK1KDM4E | |
| SCHEMBL10480569 | 0.60 | MEN1 (0.51) | ALDH1A1L3MBTL1TDP1MAPK1GAA | |
| SCHEMBL9096157 | 0.59 | POLB (0.42) | USP2ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL3963112 | 0.58 | USP2 (0.53) | USP2ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL546118 | 0.58 | L3MBTL1 (0.57) | USP2ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL25659971 | 0.57 | RYR2 (0.45) | ALDH1A1KDM4EMEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396620-B1 | AMINOMETHYL-CHROMAN AND -THIOCHROMAN COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-11 | — | — | EP | claimed |