Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536170 | 0.85 | MAPT (0.52) | MAPTALDH1A1PLA2G1BATG4BKMT2A | |
| SCHEMBL9537454 | 0.85 | GHSR (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9534238 | 0.81 | POLB (0.45) | MAPTKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL9533383 | 0.77 | GPBAR1 (0.51) | MAPTKMT2AMEN1NPC1MAPK1 | |
| SCHEMBL9535755 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1SMN1; SMN2TP53MAPK1 | |
| SCHEMBL9533937 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9533918 | 0.71 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9535442 | 0.71 | GPBAR1 (0.51) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9533388 | 0.70 | TSHR (0.51) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9533884 | 0.70 | KMT2A (0.59) | MAPTALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |