Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577833 | 0.77 | — | — | |
| SCHEMBL9536253 | 0.73 | FDPS (0.45) | ALDH1A1SMN1; SMN2FDPSMEN1KMT2A | |
| SCHEMBL29180050 | 0.70 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL9537489 | 0.69 | FDPS (0.42) | ALDH1A1SMN1; SMN2FDPSKCNA5KCNE1 | |
| SCHEMBL9715445 | 0.68 | L3MBTL1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL18939567 | 0.67 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9537775 | 0.67 | NPC1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| Oxalic Acid SCHEMBL9536045 | 0.67 | USP2 (0.57) | ALDH1A1SMN1; SMN2FDPSUSP2LMNA | |
| SCHEMBL23487154 | 0.67 | FDPS (0.47) | ALDH1A1SMN1; SMN2FDPSMEN1KMT2A | |
| SCHEMBL13574526 | 0.67 | FDPS (0.47) | ALDH1A1SMN1; SMN2FDPSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |