Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543538 | 0.82 | NPC1 (0.45) | SLC6A9NPC1RAB9ATRPM8SLC6A2 | |
| SCHEMBL10453097 | 0.76 | SLC6A9 (0.51) | SLC6A9NPC1RAB9ATRPM8SLC6A2 | |
| SCHEMBL9541760 | 0.70 | TUBB4A (0.51) | SLC6A9MAPTMEN1KMT2APOLB | |
| SCHEMBL12917871 | 0.70 | ALDH1A1 (0.58) | SLC6A9NPC1RAB9AMAPTTSHR | |
| SCHEMBL9540784 | 0.70 | MEN1 (0.47) | SLC6A9RAB9ATRPM8SLC6A2SLC6A4 | |
| SCHEMBL10453321 | 0.70 | MAPT (0.50) | SLC6A9TRPM8SLC6A2SLC6A4MAPT | |
| SCHEMBL9542226 | 0.69 | TRPM8 (0.47) | SLC6A9TRPM8SLC6A2SLC6A4MAPT | |
| SCHEMBL9208637 | 0.67 | SLC6A9 (0.44) | SLC6A9SLC6A2SLC6A4MAPTPDK2 | |
| SCHEMBL3233715 | 0.66 | HSD11B1 (0.71) | PDK2HSD11B1 | |
| SCHEMBL9544578 | 0.66 | TRPM8 (0.47) | SLC6A9NPC1RAB9ATRPM8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |