Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543530 | 0.82 | SLC6A9 (0.38) | NPC1RAB9ATRPM8SLC6A9TSHR | |
| SCHEMBL10453097 | 0.79 | SLC6A9 (0.51) | NPC1RAB9ATRPM8SLC6A9SLC6A2 | |
| SCHEMBL9541760 | 0.73 | TUBB4A (0.51) | SLC6A9MAPTMEN1KMT2A | |
| SCHEMBL9540784 | 0.73 | MEN1 (0.47) | RAB9ATRPM8SLC6A9SLC6A2SLC6A4 | |
| SCHEMBL12917871 | 0.73 | ALDH1A1 (0.58) | NPC1RAB9ASLC6A9TSHRMAPT | |
| SCHEMBL9542254 | 0.72 | TRPM8 (0.55) | NPC1RAB9ATRPM8TSHRKDM4E | |
| SCHEMBL9544546 | 0.72 | TRPM8 (0.55) | NPC1RAB9ATRPM8TSHRKDM4E | |
| SCHEMBL10453321 | 0.72 | MAPT (0.50) | TRPM8SLC6A9TSHRSLC6A2SLC6A4 | |
| SCHEMBL9542226 | 0.72 | TRPM8 (0.47) | TRPM8SLC6A9SLC6A2SLC6A4PDK2 | |
| SCHEMBL9544578 | 0.70 | TRPM8 (0.47) | NPC1RAB9ATRPM8SLC6A9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |