Hydrogen Peroxide

Hydrogen Peroxide

SCHEMBL11036237

CC(C)c1ccc(S(=O)(=O)[O-])cc1.[Na+].[Na+].[O-]O

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrogen Peroxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 1/20 0.46
CA1 known ✓ P00915 1/20 0.46
CA2 known ✓ P00918 1/20 0.46
LMNA P02545 4/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
CA9 Q16790 1/20 0.46
MCOLN3 Q8TDD5 1/20 0.46
NR1I2 O75469 1/20 0.45
TYR P14679 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
KAT6A Q92794 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67964 0.96 ALDH1A1 (0.50) LMNAALDH1A1MAPTKDM4EGAA
Sulfuric Acid SCHEMBL8078542 0.94 LMNA (0.46) LMNAALDH1A1MAPTKDM4EGAA
SCHEMBL8406672 0.93 ALDH1A1 (0.48) LMNAALDH1A1MAPTKDM4EGAA
Sulfuric Acid SCHEMBL8103454 0.93 ALDH1A1 (0.48) LMNAALDH1A1MAPTKDM4EGAA
SCHEMBL5153019 0.91 ALDH1A1 (0.50) LMNAALDH1A1MAPTKDM4EGAA
SCHEMBL1589913 0.91 ALDH1A1 (0.50) LMNAALDH1A1MAPTKDM4EGAA
Potassium Ion SCHEMBL338736 0.91 ALDH1A1 (0.50) LMNAALDH1A1MAPTKDM4EGAA
Zinc Ion SCHEMBL1589972 0.91 ALDH1A1 (0.50) LMNAALDH1A1MAPTKDM4EGAA
Tetramethylammonium Ion SCHEMBL7046620 0.87 ALDH1A1 (0.47) LMNAALDH1A1MAPTKDM4EGAA
Potassium Ion SCHEMBL9548465 0.86 ALDH1A1 (0.47) LMNAALDH1A1MAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0039633-B1 MONOPHASE PROCESS FOR THE POLYMERIZATION OF ETHYLENE IN THE PRESENCE OF WATER Société Chimique des Charbonnages (FR) 1984-07-11 EP claimed
US-4379068-A Hydrophilic cotelomers having a terminal sulfonate group and containing acid and amine functions, and their application in detergent compositions SOCIETE CHIMIQUE DES CHARBONNAGES (FR) 1983-04-05 US disclosed
US-4294717-A BLEACHES, HYDROPEROXIDATION SOCIETE CHIMIQUE DES CHARBONNAGES SA (FR) 1981-10-13 US disclosed