Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557154 | 0.80 | FKBP1A (0.64) | FKBP1AKMT2AMEN1ALDH1A1MAOA | |
| SCHEMBL9557252 | 0.78 | MAOA (0.54) | FKBP1AKMT2AMEN1ALDH1A1MAOA | |
| SCHEMBL9557084 | 0.78 | MAOA (0.56) | KMT2AMEN1ALDH1A1MAOAMAOB | |
| SCHEMBL28034769 | 0.75 | POLB (0.54) | MAOAPOLBMAPTLMNAHTR1A | |
| SCHEMBL9557185 | 0.75 | MAOA (0.53) | FKBP1AKMT2AMEN1ALDH1A1MAOA | |
| SCHEMBL9557091 | 0.74 | MAOA (0.52) | FKBP1AKMT2AMEN1ALDH1A1MAOA | |
| SCHEMBL9557043 | 0.71 | NPC1 (0.54) | FKBP1AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9556700 | 0.70 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAOAMAPT | |
| SCHEMBL28990846 | 0.69 | POLB (0.62) | FKBP1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9557059 | 0.69 | RAB9A (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |