Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556940 | 0.92 | NAAA (0.48) | ALDH1A1KMT2AMEN1NAAAAKR1C3 | |
| SCHEMBL9557043 | 0.85 | NPC1 (0.54) | ALDH1A1KMT2AMEN1NPC1TDP1 | |
| SCHEMBL9557154 | 0.85 | FKBP1A (0.64) | ALDH1A1KMT2AMEN1MAPK1NPC1 | |
| SCHEMBL9556919 | 0.80 | NAAA (0.50) | ALDH1A1KMT2AMEN1NPC1NAAA | |
| SCHEMBL10195731 | 0.80 | NPC1 (0.70) | ALDH1A1KMT2AMEN1NPC1TDP1 | |
| SCHEMBL8701414 | 0.78 | NPC1 (0.68) | ALDH1A1KMT2AMEN1NPC1TDP1 | |
| SCHEMBL9556903 | 0.77 | MAOA (0.51) | ALDH1A1NPC1NAAA | |
| SCHEMBL9556995 | 0.77 | SIGMAR1 (0.40) | NPC1 | |
| SCHEMBL9557059 | 0.77 | RAB9A (0.51) | ALDH1A1KMT2AMEN1NPC1TDP1 | |
| SCHEMBL10195733 | 0.77 | KMT2A (0.57) | ALDH1A1KMT2AMEN1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |