Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568122 | 0.94 | CTSS (0.43) | ITGB3ITGA2BCTSSRAB9ANPC1 | |
| SCHEMBL9568131 | 0.83 | CTSS (0.37) | CTSSCASP1RAB9ANPC1CTSL | |
| SCHEMBL2247378 | 0.76 | ADAMTS5 (0.59) | ITGB3ITGA2BCTSSRAB9ANPC1 | |
| SCHEMBL2247765 | 0.76 | ADAMTS5 (0.59) | ITGB3ITGA2BCTSSRAB9ANPC1 | |
| SCHEMBL8886008 | 0.76 | MAPT (0.49) | ITGB3ITGA2BCTSSRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8885572 | 0.75 | ITGB3 (0.56) | ITGB3ITGA2BRAB9ANPC1PRSS1 | |
| Hydrochloric Acid SCHEMBL8886078 | 0.74 | ITGB3 (0.59) | ITGB3ITGA2BALDH1A1PRSS1TMPRSS15 | |
| SCHEMBL7798884 | 0.70 | ALDH1A1 (0.58) | CTSSRAB9ANPC1CTSLKMT2A | |
| SCHEMBL2247441 | 0.70 | CTSS (0.52) | CTSSRAB9ANPC1CTSLADAMTS4 | |
| SCHEMBL9251560 | 0.69 | ITGB3 (0.47) | ITGB3ITGA2BCTSSRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |