Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705802 | 0.85 | CES2 (0.36) | CES2CES1BCHEALBERN1 | |
| SCHEMBL7156428 | 0.83 | CES2 (0.39) | CES2CES1BCHEALBERN1 | |
| SCHEMBL21201383 | 0.83 | ACHE (0.48) | CES2CES1BCHEALDH1A1PKM | |
| SCHEMBL6151711 | 0.83 | CYP3A4 (0.35) | CES2CES1BCHEALDH1A1HPGD | |
| SCHEMBL535572 | 0.83 | TAAR1 (0.41) | CES2CES1ALDH1A1KDM4EHPGD | |
| SCHEMBL7703149 | 0.81 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL2960326 | 0.78 | NFE2L2 (0.43) | BCHEALDH1A1KDM4EACHEHPGD | |
| SCHEMBL8994176 | 0.74 | CES2 (0.37) | CES2CES1BCHE | |
| SCHEMBL18245283 | 0.71 | CES2 (0.36) | CES2CES1BCHEALBERN1 | |
| SCHEMBL95722 | 0.71 | CES2 (0.37) | CES2CES1ERN1ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117903168-A | Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| WO-2023036707-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-16 | — | — | WO | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| CN-110483328-A | 2,6- bis- (amino-benzene oxygen)-N- [4- (phenylazo) phenyl] benzamide monomer and preparation method | ANYANG INST TECH | 2019-11-22 | — | — | CN | claimed |
| CN-110437096-A | The preparation method of 2,6- bis- (amino-benzene oxygen)-N- (2- aminofluorene) benzamide monomer | ANYANG INST TECH | 2019-11-12 | — | — | CN | claimed |
| US-10172350-B2 | Substituted 5-hydroxy-2-phenyl-3-heteroaryl pentanenitrile derivatives, method for the production thereof and use thereof as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-08 | — | — | US | claimed |
| CN-108864075-A | A kind of isothiazole connection thiazole and its preparation method and application | 南开大学 | 2018-11-23 | — | — | CN | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| WO-1997036485-A1 | INSECTICIDAL COMBINATION EFFECTIVE AGAINST FLEAS ON MAMMALS, PARTICULARLY CATS AND DOGS | MERIAL (FR) | 1997-10-09 | — | — | WO | claimed |
| EP-0560268-B1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-01-04 | — | — | EP | claimed |
| EP-0560268-A1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | claimed |
| EP-0323637-B1 | L(-) 2,6-DIFLUOROBENZOIC-N-(1,1,1-TRIFLUORO-PROP-2-YL)AMIDE | BAYER AG (DE) | 1992-12-16 | — | — | EP | claimed |
| EP-0281186-B1 | PROCESS FOR THE PREPARATION OF A BENZOIC ACID DERIVATIVE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-10-28 | — | — | EP | claimed |
| EP-0189960-B1 | NOVEL INSECTICIDAL 1,3-THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-04-24 | — | — | EP | claimed |
| EP-0271923-B1 | N-(2,6-difluorobenzoyl)-N'-3-chloro-4-[1,1,2-trifluoro-2-(trifluoromethoxy) ethoxy] phenyl urea having insecticidal activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1990-08-22 | — | — | EP | claimed |
| EP-0323637-A1 | L(-) 2,6-difluorobenzoic-N-(1,1,1-trifluoro-prop-2-yl)amide | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| EP-0088343-B1 | UREA DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | CES2 4108/4885CES1 4462/4885BCHE 3781/4885 |
| US-10172350-B2 | Substituted 5-hydroxy-2-phenyl-3-heteroaryl pentanenitrile derivatives, method for the production thereof and use thereof as herbicides and/or plant growth regulators | HPD, HAAO, GRHPR | CES2 585/4885CES1 309/4885BCHE 691/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | CES2 4108/4885CES1 4462/4885BCHE 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.