Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633509 | 0.72 | — | — | |
| SCHEMBL424538 | 0.71 | IDO1 (0.46) | ALDH1A1SMN1; SMN2ACHEIDO1TDO2 | |
| SCHEMBL11201293 | 0.70 | ACHE (0.62) | GAAALDH1A1SMN1; SMN2ACHEMEN1 | |
| SCHEMBL827163 | 0.69 | — | — | |
| SCHEMBL14923162 | 0.68 | — | — | |
| SCHEMBL7550562 | 0.67 | ALOX5 (0.41) | ALOX5KDM4ESLC6A3CYP2C19 | |
| SCHEMBL7320913 | 0.67 | SLC6A3 (0.41) | GAAALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL10357652 | 0.67 | ESR1 (0.41) | GAAALDH1A1ACHEPOLBIDO1 | |
| SCHEMBL7072983 | 0.64 | ALOX5 (0.41) | ALOX5ADRA1DALDH1A1POLBMEN1 | |
| SCHEMBL6315132 | 0.64 | ALOX5 (0.41) | ALOX5ADRA1DGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177077-A | Inhibitors at dopamine uptake sites, treatment of mental disorders | NOVO NORDISK A/S (DK) | 1993-01-05 | — | — | US | disclosed |