Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9603075 | 0.79 | SLC6A2 (0.64) | DRD3HTR2AHTR1ADRD4DRD2 | |
| SCHEMBL9602967 | 0.78 | SIGMAR1 (0.79) | DRD2SIGMAR1CYP1A2GAACYP2C9 | |
| Fumaric Acid SCHEMBL9601866 | 0.77 | DRD4 (0.60) | DRD3HTR2AHTR1ADRD4HTR7 | |
| Fumaric Acid SCHEMBL9601877 | 0.77 | DRD4 (0.60) | DRD3HTR2AHTR1ADRD4HTR7 | |
| SCHEMBL9601882 | 0.77 | SIGMAR1 (0.56) | DRD3HTR2AHTR1ADRD4HTR7 | |
| Hydrochloric Acid SCHEMBL9603058 | 0.76 | DRD2 (0.79) | DRD3HTR2AHTR1ADRD4HTR7 | |
| SCHEMBL5023694 | 0.76 | DRD2 (0.65) | DRD3HTR2AHTR1ADRD4DRD2 | |
| SCHEMBL9601079 | 0.75 | HSD11B1 (0.57) | DRD3HTR2AHTR1ADRD4HTR7 | |
| SCHEMBL5864076 | 0.75 | DRD4 (0.57) | DRD3HTR2AHTR1ADRD4HTR7 | |
| SCHEMBL9602079 | 0.74 | SLC6A9 (0.55) | DRD3HTR2AHTR1AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308476-B1 | BISPHENYLALKYLPIPERAZINE DERIVATIVES, A METHOD OF THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Kabi Pharmacia AB (SE) | 1993-02-03 | — | — | EP | disclosed |