Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270539 | 0.85 | ABCG2 (0.40) | ABCG2LMNATDP1MAPTHTT | |
| SCHEMBL125466 | 0.83 | MEN1 (0.44) | LMNAMAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL80527 | 0.83 | MEN1 (0.47) | LMNAMAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL4900598 | 0.83 | MEN1 (0.47) | LMNAMAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL8412982 | 0.81 | NPC1 (0.38) | MAPTHTTALDH1A1HPGDCYP3A4 | |
| SCHEMBL9622140 | 0.81 | MAPT (0.46) | TDP1MAPTHTTNPSR1CYP1A2 | |
| SCHEMBL146203 | 0.79 | ADORA3 (0.41) | LMNAHTTNPSR1CYP1A2CYP2C19 | |
| SCHEMBL81224 | 0.78 | CXCL12 (0.43) | ABCG2LMNAMAPTHTTNPSR1 | |
| SCHEMBL25985511 | 0.77 | L3MBTL1 (0.54) | ABCG2LMNATDP1MAPTHTT | |
| SCHEMBL7518324 | 0.77 | MEN1 (0.41) | LMNAMAPTHTTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | claimed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | claimed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | claimed |
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | disclosed |
| EP-0389236-A2 | Photopolymerisable composition | Horsell Plc (GB) | 1990-09-26 | — | — | EP | disclosed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | disclosed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | disclosed |