Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633486 | 0.86 | LMNA (0.39) | LMNAKDM5AHDAC3HDAC4HDAC1 | |
| SCHEMBL9633174 | 0.80 | LMNA (0.41) | LMNAKDM5AHDAC3HDAC4HDAC1 | |
| SCHEMBL9633149 | 0.79 | LMNA (0.48) | LMNAKDM5AHDAC11PHF8DNM1 | |
| SCHEMBL9633089 | 0.79 | PAOX (0.42) | LMNAKDM5AHDAC3HDAC4HDAC1 | |
| SCHEMBL9633433 | 0.78 | FAAH (0.48) | DNM1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL9817192 | 0.73 | LMNA (0.48) | LMNAKDM5AHDAC3HDAC4HDAC1 | |
| SCHEMBL9817184 | 0.73 | LMNA (0.48) | LMNAKDM5AHDAC3HDAC4HDAC1 | |
| SCHEMBL21886876 | 0.73 | LMNA (0.48) | LMNAKDM5APHF8KDM4CFAAH | |
| SCHEMBL3425770 | 0.73 | DNM1 (0.46) | LMNAHDAC11DNM1MEN1KMT2A | |
| SCHEMBL24859122 | 0.72 | LMNA (0.38) | LMNAKDM5AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |