Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 3/20 | 0.32 |
| ▸ | SDHB | P21912 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63292 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2GLP1RSDHBAURKA | |
| SCHEMBL11585339 | 0.75 | LMNA (0.44) | LMNASMN1; SMN2GLP1RSDHBAURKA | |
| SCHEMBL6296316 | 0.75 | LMNA (0.44) | LMNASMN1; SMN2GLP1RSDHBAURKA | |
| SCHEMBL8597269 | 0.73 | LMNA (0.42) | LMNASMN1; SMN2GLP1RSDHBAURKA | |
| SCHEMBL11107779 | 0.73 | LMNA (0.47) | LMNASMN1; SMN2PTGS2GLP1RSDHB | |
| SCHEMBL13703901 | 0.73 | LMNA (0.42) | LMNASMN1; SMN2GLP1RSDHBAURKA | |
| SCHEMBL29950842 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2MEN1POLBHPGDMAPK1 | |
| SCHEMBL27846488 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2MEN1POLBHPGDMAPK1 | |
| SCHEMBL8666206 | 0.72 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2GLP1RMEN1S1PR4 | |
| SCHEMBL6885462 | 0.71 | CCR1 (0.34) | LMNAS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175261-A | Useful for coloring cellulose materials, animal furs or leather | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-29 | — | — | US | disclosed |
| EP-0471454-A1 | Reactive pyridone azo dyestuffs | ZENECA LIMITED (GB) | 1992-02-19 | — | — | EP | disclosed |