Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | GSK3B | P49841 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960793 | 0.85 | HPGD (0.55) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| SCHEMBL20097994 | 0.83 | HPGD (0.70) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| SCHEMBL8792913 | 0.82 | HPGD (0.60) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| SCHEMBL13398659 | 0.82 | L3MBTL1 (0.52) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| SCHEMBL7839202 | 0.81 | ALDH1A1 (0.52) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| Phenacyl Chloride SCHEMBL55444 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| Phenacyl Chloride SCHEMBL2314766 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 | |
| SCHEMBL4256193 | 0.81 | SMN1; SMN2 (0.63) | ALDH1A1MAPK1HPGDMEN1KMT2A | |
| SCHEMBL2775289 | 0.81 | GSK3B (0.67) | ALDH1A1GSK3BMAPK1HPGDMEN1 | |
| SCHEMBL17946314 | 0.80 | HSD17B3 (0.55) | ALDH1A1GSK3BHIF1AMAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786757-B1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD (CN) | 2017-08-16 | — | — | EP | disclosed |
| US-9156801-B2 | 2-substituted oleanolic acid derivative, method preparing for same, and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-10-13 | — | — | US | disclosed |
| US-20140343064-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | Hanghzhou Bensheng Pharmaceutical Co., Ltd (CN) | 2014-11-20 | — | — | US | disclosed |
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-30 | — | — | US | disclosed |
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-30 | — | — | US | disclosed |
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-30 | — | — | US | disclosed |
| EP-2786982-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786982-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786757-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | Hangzhou Bensheng Pharmaceutical Co., Ltd. (CN) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013004190-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国医学科学院药物研究所 (CN) | 2013-01-10 | — | — | WO | disclosed |
| EP-0306411-B1 | ETHANONE OXIMES | MITSUBISHI KASEI CORPORATION (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-4977151-A | ANTIULCER AGENTS | MITSUBISHI KASEI CORPORATION (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4933344-A | ANTIULCER AGENTS | MITSUBISHI KASEI CORPORATION (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0306411-A2 | Ethanone oximes | MITSUBISHI KASEI CORPORATION (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0020970-A1 | Alpha-chloroacetophenonoxime ethers and process for their preparation | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323501-A1 | AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | AADAT, HPGDS, HLA-DRB1 | ALDH1A1 2654/4885GSK3B 4219/4885HIF1A 609/4885 |
| US-20140343064-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | CYP27A1, SOAT2, OSBP2 | ALDH1A1 353/4885GSK3B 2782/4885HIF1A 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.