Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.48 |
| ▸ | CA1 | P00915 | 15/20 | 0.48 |
| ▸ | CA9 | Q16790 | 11/20 | 0.48 |
| ▸ | CA12 | O43570 | 9/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 6/20 | 0.44 |
| ▸ | CA7 | P43166 | 6/20 | 0.44 |
| ▸ | CA5A | P35218 | 4/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324798 | 0.84 | CA2 (0.42) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9672235 | 0.76 | KMT2A (0.45) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9299658 | 0.76 | DUT (0.48) | CA2CA7SMN1; SMN2 | |
| SCHEMBL9502675 | 0.74 | CA2 (0.51) | CA2CA1CA9CA4CA7 | |
| SCHEMBL9501062 | 0.74 | GBA1 (0.44) | CA9CA12MAPTSMN1; SMN2 | |
| SCHEMBL9673430 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2 | |
| SCHEMBL9502025 | 0.74 | ALDH1A1 (0.47) | CA2CA9CA12SMN1; SMN2 | |
| SCHEMBL9503647 | 0.73 | LMNA (0.48) | CA2CA1MAPT | |
| SCHEMBL9303870 | 0.72 | CA2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL10690610 | 0.66 | CA2 (0.89) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |