Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368214 | 0.88 | MAPT (0.39) | ALDH1A1TSHRKDM4EKMT2AMAPT | |
| SCHEMBL9680953 | 0.83 | AGTR2 (0.35) | ALDH1A1TSHRL3MBTL1KMT2AMAPT | |
| SCHEMBL9343229 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ALOX15TSHRKDM4ETDP1 | |
| SCHEMBL9343827 | 0.78 | BCAT2 (0.46) | ALDH1A1ALOX15TSHRKDM4ETDP1 | |
| SCHEMBL9343968 | 0.78 | GABRG2 (0.55) | ALDH1A1ALOX15KDM4ETDP1KMT2A | |
| SCHEMBL10367683 | 0.76 | MTNR1A (0.41) | ALDH1A1KDM4EHSD17B10KMT2AMAPT | |
| SCHEMBL7284938 | 0.76 | MAPT (0.40) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10367071 | 0.76 | ALDH1A1 (0.34) | ALDH1A1TSHRKDM4ETDP1HSD17B10 | |
| SCHEMBL9343419 | 0.75 | KMT2A (0.50) | ALDH1A1ALOX15TSHRKDM4ETDP1 | |
| SCHEMBL10368537 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472166-A1 | Tricyclic pyridone derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-26 | — | — | EP | disclosed |