Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682641 | 0.85 | CCKBR (0.37) | CCKBRMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL9499330 | 0.83 | CCKBR (0.58) | CCKBRMEN1KMT2AOPRK1NPC1 | |
| SCHEMBL9499432 | 0.75 | OPRM1 (0.49) | CCKBROPRK1NPC1RAB9A | |
| SCHEMBL9500460 | 0.71 | OPRD1 (0.60) | CCKBROPRK1 | |
| SCHEMBL9501442 | 0.70 | CCKBR (0.62) | CCKBRMEN1KMT2AHTR2COPRK1 | |
| SCHEMBL9501463 | 0.68 | LMNA (0.52) | CCKBRKMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9501031 | 0.67 | CCKBR (0.64) | CCKBRHTR2AOPRK1TP53SMN1; SMN2 | |
| SCHEMBL9501458 | 0.63 | ALDH1A1 (0.36) | CCKBRMEN1KMT2ALMNANPC1 | |
| SCHEMBL11683129 | 0.61 | HTR2C (0.46) | MEN1KMT2APTAFRHTR2AHTR2C | |
| SCHEMBL30465833 | 0.59 | PTAFR (0.42) | MEN1KMT2APTAFRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486271-A2 | Cholecystokinin antagonists for treating neurological disorders | MERCK & CO. INC. (US) | 1992-05-20 | — | — | EP | disclosed |