Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | BCL2 | P10415 | 4/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685898 | 0.97 | BCL2 (0.39) | MCL1BCL2MAP2K7CDC25ACDC25B | |
| SCHEMBL29036115 | 0.77 | MCL1 (0.46) | MCL1BCL2MAP2K7CDC25ACDC25B | |
| SCHEMBL29117498 | 0.76 | ELANE (0.55) | MCL1BCL2CDC25BKDM4EALDH1A1 | |
| SCHEMBL11294862 | 0.76 | ELANE (0.55) | MCL1BCL2MAP2K7CDC25ACDC25B | |
| SCHEMBL9849269 | 0.74 | ELANE (0.53) | MCL1BCL2CDC25BKDM4EALDH1A1 | |
| SCHEMBL9811057 | 0.74 | ELANE (0.53) | MCL1BCL2MAP2K7CDC25ACDC25B | |
| SCHEMBL27053415 | 0.73 | MAOA (0.53) | MCL1BCL2KDM4EALDH1A1GAA | |
| SCHEMBL9685867 | 0.72 | S100A4 (0.57) | MCL1BCL2ESR1ESR2MAOA | |
| SCHEMBL9685915 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDTSHRELANE | |
| SCHEMBL9685874 | 0.72 | ENPP2 (0.38) | MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |