Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685943 | 0.97 | PKM (0.41) | ENPP2PARGPTGS2PKMSMN1; SMN2 | |
| SCHEMBL17948135 | 0.77 | PKM (0.53) | ENPP2PARGPKMSMN1; SMN2BRD4 | |
| SCHEMBL29117512 | 0.77 | ENPP2 (0.54) | ENPP2PTGS2 | |
| SCHEMBL29117498 | 0.76 | ELANE (0.55) | PARGSMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL7125518 | 0.76 | PARG (0.59) | PARGPTGS2PKMSMN1; SMN2MEN1 | |
| SCHEMBL9849269 | 0.74 | ELANE (0.53) | SMN1; SMN2MEN1MAPTMAPK1HTT | |
| SCHEMBL10070529 | 0.73 | PARG (0.44) | ENPP2PARGPKMSMN1; SMN2BRD4 | |
| SCHEMBL11085074 | 0.72 | ESR1 (0.62) | ENPP2PARGPKMSMN1; SMN2MEN1 | |
| SCHEMBL9685890 | 0.72 | MCL1 (0.37) | PTGS2MAPT | |
| SCHEMBL9685915 | 0.72 | ALDH1A1 (0.37) | PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |