Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | PARG | Q86W56 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685874 | 0.97 | ENPP2 (0.38) | PKMPARGMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17948135 | 0.82 | PKM (0.53) | PKMPARGALDH1A1MEN1KMT2A | |
| SCHEMBL9849269 | 0.79 | ELANE (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL29117498 | 0.77 | ELANE (0.55) | PARGALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7125518 | 0.77 | PARG (0.59) | PKMPARGALDH1A1MEN1KMT2A | |
| SCHEMBL11085074 | 0.77 | ESR1 (0.62) | PKMPARGALDH1A1MEN1KMT2A | |
| SCHEMBL9685898 | 0.74 | BCL2 (0.39) | ALDH1A1SMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL9684483 | 0.74 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL29117512 | 0.74 | ENPP2 (0.54) | ENPP2PTGS2 | |
| SCHEMBL10070529 | 0.74 | PARG (0.44) | PKMPARGALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |