Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164713 | 0.82 | MMP13 (0.48) | HPGDUSP2ALDH1A1LMNA | |
| SCHEMBL9686935 | 0.81 | CNR1 (0.47) | POLBROCK2ROCK1ALDH1A1 | |
| SCHEMBL9280239 | 0.78 | RXFP1 (0.45) | MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL9164720 | 0.70 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL9687941 | 0.69 | EZH2 (0.40) | HPGDMEN1KMT2AROCK2 | |
| SCHEMBL9278822 | 0.69 | RAB9A (0.46) | POLBHPGDRECQLMEN1KMT2A | |
| SCHEMBL9688033 | 0.69 | HTT (0.49) | POLBHPGDRECQLMEN1KMT2A | |
| SCHEMBL9416583 | 0.68 | HSD17B2 (0.74) | HSD17B2POLBHPGDRECQLMEN1 | |
| SCHEMBL15831230 | 0.68 | MEN1 (0.62) | HSD17B2POLBHPGDRECQLMEN1 | |
| SCHEMBL9687454 | 0.67 | MEN1 (0.39) | RECQLMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |