Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164713 | 0.91 | MMP13 (0.48) | MAPTALDH1A1 | |
| SCHEMBL9280239 | 0.83 | RXFP1 (0.45) | RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL9688086 | 0.81 | HSD17B2 (0.46) | ROCK2ROCK1ALDH1A1POLB | |
| SCHEMBL9687941 | 0.78 | EZH2 (0.40) | ROCK2 | |
| SCHEMBL9688033 | 0.77 | HTT (0.49) | RAB9ATP53ALDH1A1POLB | |
| SCHEMBL9687454 | 0.76 | MEN1 (0.39) | MAPTALDH1A1 | |
| SCHEMBL9687392 | 0.75 | CYP1A2 (0.46) | TP53MAPTALDH1A1POLB | |
| SCHEMBL9687409 | 0.73 | LMNA (0.43) | MAPTROCK2ROCK1 | |
| SCHEMBL9278822 | 0.73 | RAB9A (0.46) | RAB9ATP53MAPTALDH1A1POLB | |
| SCHEMBL9687391 | 0.73 | HPGD (0.39) | TP53MAPTROCK2ROCK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |