Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034843 | 0.87 | KIF11 (0.42) | KIF11RARBRARGTSHRLMNA | |
| SCHEMBL2868881 | 0.78 | KIF11 (0.56) | KIF11RARBRARGTSHRLMNA | |
| SCHEMBL25413986 | 0.78 | RARB (0.65) | KIF11RARBRARGTSHRLMNA | |
| SCHEMBL19875742 | 0.78 | KIF11 (0.56) | KIF11RARBRARGTSHRLMNA | |
| SCHEMBL7364375 | 0.77 | ALDH1A1 (0.68) | LMNAALDH1A1HDAC1SMN1; SMN2CYP1A2 | |
| SCHEMBL13676290 | 0.77 | RARB (0.53) | KIF11RARBRARGTSHRLMNA | |
| SCHEMBL3239579 | 0.77 | KIF11 (0.32) | KIF11RARBRARG | |
| SCHEMBL424728 | 0.76 | TSHR (0.73) | KIF11TSHRLMNATYRALDH1A1 | |
| SCHEMBL104811 | 0.76 | APP (0.32) | — | |
| SCHEMBL1611698 | 0.76 | KIF11 (0.54) | KIF11RARBRARGTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| CN-113929695-B | Sulfimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | claimed |
| US-11358937-B2 | Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2022-06-14 | — | — | US | claimed |
| CN-112028811-B | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | claimed |
| CN-112028812-B | 4-bromoindole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | claimed |
| CN-112028813-B | 4-chloro indole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | claimed |
| CN-113929695-A | Sulfenimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2022-01-14 | — | — | CN | claimed |
| CN-113698312-A | Synthetic method of aromatic amide alkene compound | 南京先进生物材料与过程装备研究院有限公司 | 2021-11-26 | — | — | CN | claimed |
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| US-4286088-A | Process for preparing 7-aminocephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-08-25 | — | — | US | claimed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | claimed |
| EP-0011288-A1 | p-Tert.-butylbenzotribromide and his derivatives which are substituted in the ring by halogen, a process for their preparation as well as their use. | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | claimed |
| US-4166178-A | 3-ACYLOXYMETHYL-CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-08-28 | — | — | US | claimed |
| US-4068071-A | DISULFIDING, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| US-4068072-A | CHLORINATION OR BROMINATION, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| US-4011214-A | 3-(MORPHOLINOALKOXYIMINOMETHYL)CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-08 | — | — | US | claimed |
| US-4003875-A | ULTRAVIOLET ABSORBERS | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | claimed |
| US-3984401-A | Process for producing lactol-type cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358937-B2 | Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers | ADAR, SPOUT1, RNGTT | KIF11 1656/4885RARB 4313/4885RARG 4426/4885 |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | CHP1, NFATC1, PPP3R1 | KIF11 4622/4885RARB 4284/4885RARG 4546/4885 |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | KIF11 4622/4885RARB 4284/4885RARG 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.