Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.57 |
| ▸ | BCL2 | P10415 | 5/20 | 0.57 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713573 | 0.88 | MAOA (0.55) | MCL1BCL2MAOAMAOBS100A4 | |
| SCHEMBL9713712 | 0.84 | DDAH1 (0.41) | MCL1BCL2MAOAMAOBCDC25B | |
| SCHEMBL9628309 | 0.82 | S100A4 (0.52) | MCL1BCL2S100A4PTPRCAURKA | |
| SCHEMBL9713721 | 0.81 | P4HB (0.44) | MCL1BCL2MAOAMAOBPTPN1 | |
| SCHEMBL9713750 | 0.80 | MAPT (0.45) | MCL1BCL2MAOAMAOBS100A4 | |
| SCHEMBL9713431 | 0.78 | BCL2 (0.54) | MCL1BCL2MAOAMAOBPTPN1 | |
| SCHEMBL9713415 | 0.77 | BCL2 (0.39) | MCL1BCL2MAOAMAOBPTPN1 | |
| SCHEMBL9713724 | 0.73 | L3MBTL1 (0.50) | MCL1BCL2MAOAMAOB | |
| SCHEMBL9713331 | 0.72 | SLC6A4 (0.39) | MCL1BCL2S100A4 | |
| SCHEMBL8773066 | 0.71 | S100A4 (0.56) | PTPN1S100A4PTPRCAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |