Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713573 | 0.86 | MAOA (0.55) | MAOAMAOBBCL2MCL1AURKA | |
| SCHEMBL9713334 | 0.84 | MCL1 (0.57) | MAOAMAOBBCL2MCL1CDC25B | |
| SCHEMBL9713721 | 0.80 | P4HB (0.44) | MAOAMAOBBCL2MCL1PTGS2 | |
| SCHEMBL9713750 | 0.79 | MAPT (0.45) | MAOAMAOBBCL2MCL1PDE7A | |
| SCHEMBL9713724 | 0.78 | L3MBTL1 (0.50) | MAOAMAOBBCL2MCL1PDE7A | |
| SCHEMBL9713415 | 0.75 | BCL2 (0.39) | MAOAMAOBBCL2MCL1PDE7A | |
| SCHEMBL9714218 | 0.72 | NPC1 (0.36) | BCL2MCL1 | |
| SCHEMBL9713331 | 0.71 | SLC6A4 (0.39) | BCL2MCL1 | |
| SCHEMBL8773066 | 0.70 | S100A4 (0.56) | AURKAAURKB | |
| SCHEMBL9713780 | 0.69 | IDO1 (0.50) | MAOAMAOBBCL2MCL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |